ponce@caltech.edu
Bacterial spores (endospores) are the most resistant forms of life, capable
of surviving environmental extremes such as temperature, desiccation, and radiation.
Reports indicate that endospores can survive for years in space, and can be
revived after lying dormant for thousands of years. Our primary scientific
objective is to determine endospore viability in the most extreme environments
on Earth. To this end, we recently demonstrated a novel endospore viability
assay (EVA) capable of quantifying the viable fraction of endospores embedded
in desert soils, permafrost, and ice cores. Research opportunities are available
in (1) analytical chemistry for optimization of the detection chemistry, (2)
microbiology for the study of endospores in extreme environments, and (3) field-instrument
development for deployment in extreme environments. The endospore detection
technology also finds immediate application in biodefense (Anthrax Smoke Detector),
validation of bioburden reduction on spacecraft (Planetary Protection), and
microbial event monitoring on the international space station.
No experience required, only enthusiasm for learning new science and technology.
This work will be performed in a multipurpose laboratory, containing laser
systems, chemicals, and non-disease causing microorganisms. Corresponding safety
classes will be required, which will be arranged by the SURF office and/or
Adrian Ponce. For additional information regarding research in the group please
visit my web page at ponce.caltech.edu or
contact me via e-mail.
